Categorizing diffuse parenchymal lung disease in children

Categorizing diffuse parenchymal lung disease in children

BACKGROUND Aim of this study was to verify a systematic and practical categorization system that allows dynamic classification of pediatric DPLD irrespective of completeness of patient data. METHODS The study was based on 2322 children submitted to the kids-lung-register between 1997 and 2012. Of these children 791 were assigned to 12 DPLD categories, more than 2/3 belonged to categories mani...

DIFFUSE PARENCHYMAl lUNG DISEASE

Diffuse parenchymal lung disease (DPLD) is a group of diseases that have the common characteristic of involving the pulmonary parenchyma diffusely. The pulmonary parenchyma consists of all structures distal to the terminal bronchiole. DPLD are numerous, there are some 150 different entities that qualify for the group. Most of these diseases are diagnosed according to common algorithm, but the e...

Open lung biopsy for diffuse parenchymal lung disease in children.

An open lung biopsy was performed in 12 children with diffuse parenchymal lung disease. A definitive histopathological diagnosis was obtained from all procedures but determined treatment options in only 10 children (83%). Three (25%) children were ventilated for respiratory failure prior to the procedure. Four (44%) of the other 9 children required ventilatory support after the procedure. Three...

Clonorchiasis Complicated with Diffuse Parenchymal Lung Disease in Children

Castleman disease-associated diffuse parenchymal lung disease

Intrathoracic involvement is common in Castleman disease (CD), but CD-associated diffuse parenchymal lung disease (DPLD) is rare and not well-reported.We conducted a retrospective analysis of 262 CD patients with a definite pathological diagnosis who were hospitalized between 1999 and 2015.Twenty-two CD patients had DPLD based on chest computed tomography (CT) scans. Among them, 9 were male and...